Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | ILK | Q13418 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801257 | 0.99 | NPC1 (0.60) | NPC1RAB9ACYP19A1CYP2A6PIK3CD | |
| SCHEMBL17801340 | 0.83 | NPC1 (0.61) | NPC1RAB9ACYP19A1CYP2A6PIK3CD | |
| SCHEMBL17801198 | 0.82 | RAB9A (0.60) | NPC1RAB9ACYP19A1CYP2A6PIK3CD | |
| SCHEMBL17801374 | 0.78 | NPC1 (0.56) | NPC1RAB9ACYP19A1CYP2A6PIK3CD | |
| SCHEMBL17801186 | 0.77 | RAB9A (0.62) | NPC1RAB9ACYP19A1CYP2A6PIK3CD | |
| SCHEMBL17801309 | 0.77 | NPC1 (0.55) | NPC1RAB9APIK3CDPIP5K1CPIK3CA | |
| SCHEMBL20519963 | 0.77 | RAB9A (0.76) | NPC1RAB9ACYP19A1CYP2A6PIK3CD | |
| SCHEMBL24366502 | 0.77 | NPC1 (0.66) | NPC1RAB9ACYP19A1CYP2A6ALOX5 | |
| SCHEMBL21589907 | 0.76 | APP (0.43) | NPC1RAB9A | |
| SCHEMBL17812983 | 0.76 | NPC1 (0.59) | NPC1RAB9ACYP19A1PIK3CDPIP5K1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227301-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087417-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |