Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058294 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6277586 | 0.82 | KMT2A (0.55) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7568792 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL17801474 | 0.78 | MAPT (0.39) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL7547167 | 0.75 | BACE1 (0.46) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL5781932 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| SCHEMBL20472500 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL30468364 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL6588228 | 0.73 | MAPT (0.49) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL31716582 | 0.73 | BACE1 (0.43) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |