Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | PGK1 | P00558 | 4/20 | 0.41 |
| ▸ | PGK2 | P07205 | 4/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2921664 | 0.83 | HDAC4 (0.42) | KIF11TAAR1MAOASLC6A2SLC6A4 | |
| SCHEMBL9223226 | 0.83 | DAO (0.45) | DAOMRGPRX4PGK1PGK2NOTUM | |
| SCHEMBL6297454 | 0.80 | DAO (0.46) | DAOMRGPRX4PGK1PGK2NOTUM | |
| SCHEMBL21802668 | 0.79 | MEN1 (0.47) | PGK1PGK2HTR2AHTR2B | |
| SCHEMBL28874730 | 0.79 | TAAR1 (0.42) | HTR2AHTR2CHTR2BTAAR1MAOA | |
| SCHEMBL21802665 | 0.79 | MEN1 (0.47) | PGK1PGK2HTR2AHTR2B | |
| SCHEMBL13888659 | 0.78 | DAO (0.45) | DAOMRGPRX4PGK1PGK2HTR2A | |
| SCHEMBL9223232 | 0.78 | DAO (0.45) | DAOMRGPRX4PGK1PGK2NOTUM | |
| SCHEMBL9216952 | 0.78 | ENPP2 (0.45) | DAOMRGPRX4PGK1PGK2RXRA | |
| SCHEMBL9216943 | 0.78 | DAO (0.49) | DAOMRGPRX4PGK1PGK2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279933-A | Cyclic compounds having selective KRAS inhibition relative to HRAS and NRAS | 中外制药株式会社 | 2023-12-22 | — | — | CN | disclosed |
| CN-106478497-A | Aryl amine derivatives as TTX S blocker | 拉夸里亚创药株式会社 | 2017-03-08 | — | — | CN | disclosed |
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |