Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801474 | 0.83 | MAPT (0.39) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL17816502 | 0.82 | RXFP1 (0.41) | LCKBRD9RXFP1 | |
| SCHEMBL17801408 | 0.79 | BRD9 (0.38) | LCKBRD9RXFP1 | |
| SCHEMBL17801596 | 0.78 | BRD4 (0.42) | LCKBRD9HTT | |
| SCHEMBL23384409 | 0.76 | LCK (0.43) | LCKBRD9NPC1RAB9A | |
| SCHEMBL29365161 | 0.76 | LCK (0.43) | LCKBRD9NPC1RAB9A | |
| SCHEMBL30341113 | 0.76 | MEN1 (0.46) | LCKBRD9MEN1NPC1HTT | |
| SCHEMBL30046033 | 0.74 | LCK (0.43) | LCKBRD9RXFP1 | |
| SCHEMBL21783402 | 0.74 | LCK (0.43) | LCKBRD9RXFP1 | |
| SCHEMBL31487670 | 0.73 | RAB9A (0.45) | LCKBRD9MEN1NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |