SCHEMBL17802499

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17802451	0.83	NPC1 (0.44)	NPC1RAB9AKDM4EHPGDALOX5
	SCHEMBL17802446	0.80	NPC1 (0.42)	NPC1RAB9AABL1ALOX5CYP3A4
	SCHEMBL17802472	0.77	NPC1 (0.52)	NPC1RAB9AKDM4EHPGDSMN1; SMN2
	SCHEMBL17802478	0.77	RAB9A (0.52)	NPC1RAB9AKDM4ESMN1; SMN2ALOX5
	SCHEMBL17802497	0.77	NPC1 (0.47)	NPC1RAB9ANPY5RKDM4EABL1
	SCHEMBL17802441	0.77	NPC1 (0.36)	NPC1RAB9AKDM4EHPGDTSHR
	SCHEMBL17802505	0.75	CYP1A2 (0.35)	NPC1RAB9ASMN1; SMN2ABL1CYP17A1
	SCHEMBL17802464	0.75	NPC1 (0.35)	NPC1RAB9AKDM4EABL1CYP17A1
	SCHEMBL17802461	0.74	CYP1A2 (0.34)	NPC1RAB9AABL1CYP17A1CYP3A4
	SCHEMBL3752648	0.73	KDM4E (0.61)	NPC1RAB9ANPY5RKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.