SCHEMBL178025

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3726532	0.90	CXCR3 (0.54)	CXCR3KCNH2GRIN2BCCR1POLB
	SCHEMBL168793	0.89	CXCR3 (0.60)	CXCR3KCNH2GRIN2BEIF2AK3CYP3A4
	SCHEMBL3733665	0.89	CXCR3 (0.74)	CXCR3KCNH2KMT2AALDH1A1PKM
	SCHEMBL164590	0.88	CXCR3 (0.52)	CXCR3KCNH2GRIN2BEIF2AK3CYP3A4
	SCHEMBL168743	0.88	CXCR3 (0.58)	CXCR3KCNH2GRIN2BEIF2AK3CYP3A4
	SCHEMBL22965168	0.87	CXCR3 (0.60)	CXCR3KCNH2GRIN2BEIF2AK3CYP3A4
	SCHEMBL162241	0.87	CXCR3 (0.52)	CXCR3KCNH2
	SCHEMBL3742956	0.86	CXCR3 (0.59)	CXCR3KCNH2GRIN2BEIF2AK3CYP3A4
	SCHEMBL3728380	0.86	CXCR3 (0.56)	CXCR3KCNH2GRIN2BKMT2AALDH1A1
	SCHEMBL167336	0.85	CXCR3 (0.55)	CXCR3KCNH2GRIN2BEIF2AK3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.