Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 11/20 | 0.83 |
| ▸ | SUCNR1 | Q9BXA5 | 6/20 | 0.58 |
| ▸ | F11 | P03951 | 2/20 | 0.58 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16396922 | 0.91 | CFD (1.00) | CFDSUCNR1F11TPSB2CNR2 | |
| SCHEMBL17802659 | 0.89 | CFD (0.66) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL17802710 | 0.84 | CFD (0.60) | CFDSUCNR1F11TPSB2IRAK4 | |
| SCHEMBL17802739 | 0.84 | SUCNR1 (0.81) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL16397161 | 0.81 | CFD (0.78) | CFDSUCNR1F11TPSB2CNR2 | |
| SCHEMBL16396645 | 0.80 | CFD (0.81) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL16396782 | 0.80 | CFD (0.81) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL16396279 | 0.80 | CFD (0.80) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL16396505 | 0.80 | CFD (0.80) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL16396776 | 0.79 | CFD (0.77) | CFDSUCNR1F11TPSB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016088082-A1 | AMIDOMETHYL-BIARYL DERIVATIVES COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2016-06-09 | — | — | WO | claimed |
| WO-2016088082-A1 | AMIDOMETHYL-BIARYL DERIVATIVES COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2016-06-09 | — | — | WO | disclosed |