Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17803418 | 0.98 | RAB9A (0.55) | RAB9ANPC1CYP2A6KDM4EALOX5 | |
| SCHEMBL17803423 | 0.84 | NPC1 (0.55) | RAB9ANPC1CYP2A6KDM4EALOX5 | |
| SCHEMBL14693733 | 0.81 | MAOB (0.59) | RAB9ANPC1KDM4ESMN1; SMN2MAOB | |
| SCHEMBL17803424 | 0.81 | RAB9A (0.55) | RAB9ANPC1CYP2A6KDM4EALOX5 | |
| SCHEMBL19360869 | 0.81 | RAB9A (0.55) | RAB9ANPC1CYP2A6KDM4EALOX5 | |
| SCHEMBL20538690 | 0.78 | NPC1 (0.64) | RAB9ANPC1CYP2A6KDM4EALOX5 | |
| SCHEMBL17731323 | 0.78 | NPC1 (0.52) | RAB9ANPC1CYP2A6KDM4EALOX5 | |
| SCHEMBL17803453 | 0.77 | MAOB (0.72) | RAB9ANPC1CYP2A6KDM4EALOX5 | |
| SCHEMBL17803443 | 0.77 | RAB9A (0.55) | RAB9ANPC1CYP2A6KDM4EALOX5 | |
| SCHEMBL17803412 | 0.77 | RAB9A (0.51) | RAB9ANPC1CYP2A6KDM4EALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227303-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2018-10-24 | — | — | EP | disclosed |
| EP-3227303-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087418-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |