SCHEMBL1780381

SCHEMBL1780381

CC(N)P(=O)(O)CC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.73
ANPEP P15144 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6927389 1.00 MME (0.73) MMEANPEP
SCHEMBL23752212 1.00 MME (0.73) MMEANPEP
Bromide SCHEMBL6926898 0.99 MME (0.72) MMEANPEP
Bromide SCHEMBL6928095 0.94 MME (0.80) MMEANPEP
SCHEMBL12611280 0.89
SCHEMBL7615348 0.89
SCHEMBL30301323 0.88 MME (0.62) MMEANPEP
Hydrochloric Acid SCHEMBL6928493 0.88
SCHEMBL12609418 0.87 MME (0.71) MMEANPEP
SCHEMBL6927060 0.87 MME (0.71) MMEANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291599-B2 Use of inhibitors of enzymes having activities of amino peptidase N and/or dipeptidyl peptidase IV and of pharmaceutical preparations thereof for a therapy and prevention of chronical neurodegenerative diseases KEYNEUROTEK AG (DE) 2007-11-06 US claimed
US-20110117069-A1 METHOD FOR ACTIVATING REGULATORY T-CELLS IMTM GMBH (DE) 2011-05-19 US disclosed
US-20110117069-A1 METHOD FOR ACTIVATING REGULATORY T-CELLS IMTM GMBH (DE) 2011-05-19 US disclosed
US-20110117069-A1 METHOD FOR ACTIVATING REGULATORY T-CELLS IMTM GMBH (DE) 2011-05-19 US disclosed
EP-2178527-A1 METHOD FOR ACTIVATING REGULATORY T-CELLS IMTM GmbH (DE) 2010-04-28 EP disclosed
WO-2009024348-A1 METHOD FOR ACTIVATING REGULATORY T-CELLS IMTM GMBH (DE) 2009-02-26 WO disclosed
WO-2009024348-A1 METHOD FOR ACTIVATING REGULATORY T-CELLS IMTM GMBH (DE) 2009-02-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117069-A1 METHOD FOR ACTIVATING REGULATORY T-CELLS ANPEP, DNPEP, RNPEP MME 72/4885ANPEP 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.