Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6926898 | 0.96 | MME (0.72) | MMEANPEP | |
| SCHEMBL23752212 | 0.94 | MME (0.73) | MMEANPEP | |
| SCHEMBL6927389 | 0.94 | MME (0.73) | MMEANPEP | |
| SCHEMBL1780381 | 0.94 | MME (0.73) | MMEANPEP | |
| SCHEMBL1764418 | 0.89 | MME (1.00) | MMEANPEP | |
| SCHEMBL4992398 | 0.89 | MME (1.00) | MMEANPEP | |
| SCHEMBL12609398 | 0.89 | MME (1.00) | MMEANPEP | |
| SCHEMBL4992386 | 0.89 | MME (1.00) | MMEANPEP | |
| SCHEMBL20526397 | 0.89 | MME (1.00) | MMEANPEP | |
| SCHEMBL29684736 | 0.89 | MME (1.00) | MMEANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518260-B1 | (α-aminophosphino) peptide derivatives, method for making same and therapeutic applications thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2003-02-11 | — | — | US | disclosed |