Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13280030 | 0.91 | EZH2 (0.43) | EZH2CRHR1 | |
| SCHEMBL18830476 | 0.90 | CRHR1 (0.38) | EZH2CRHR1 | |
| SCHEMBL15710364 | 0.87 | EZH2 (0.45) | EZH2CRHR1 | |
| SCHEMBL18829950 | 0.82 | EZH2 (0.60) | EZH2 | |
| SCHEMBL13279996 | 0.81 | CRHR1 (0.38) | EZH2CRHR1 | |
| SCHEMBL13468559 | 0.78 | CRHR1 (0.38) | EZH2CRHR1 | |
| SCHEMBL18830160 | 0.78 | EZH2 (0.51) | EZH2CRHR1 | |
| SCHEMBL13279921 | 0.77 | EZH2 (0.39) | EZH2 | |
| SCHEMBL18829900 | 0.77 | EZH2 (0.57) | EZH2 | |
| SCHEMBL13279905 | 0.76 | EZH2 (0.77) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3165520-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme Inc (US) | 2017-05-10 | — | — | EP | disclosed |
| EP-2697198-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2016-06-08 | — | — | EP | disclosed |