SCHEMBL178053

SCHEMBL178053

C/C=C\c1ccccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30480966 1.00
SCHEMBL93619 1.00
SCHEMBL455427 1.00
Bromide SCHEMBL28229434 0.98 NPC1 (0.68)
Hydrochloric Acid SCHEMBL4201176 0.98 NPC1 (0.68)
Iodide SCHEMBL28203943 0.98 NPC1 (0.68)
Styrene SCHEMBL8437178 0.84 NPC1 (0.52)
Methyl Alcohol SCHEMBL28478479 0.84 NPC1 (0.89)
SCHEMBL2631576 0.84 NPC1 (0.62)
SCHEMBL229329 0.84 NPC1 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4141915-A REACTING AN UNSATURATED NITRILE, AN ALCOHOL, AND CARBON MONOXIDE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-02-27 US claimed
CN-108179235-B Tanning agent prepared from modified rice dialdehyde starch 温州大学 2020-09-29 CN disclosed
EP-3313837-B1 CARBOLINE ANTIPARASITICS ZOETIS SERVICES LLC (US) 2020-09-09 EP disclosed
EP-2390243-B1 PROCESS FOR PREPARING BISPHENOL MITSUBISHI CHEM CORP (JP) 2020-07-08 EP disclosed
US-10570129-B2 Carboline antiparasitics ZOETIS SERVICES LLC (US) 2020-02-25 US disclosed
US-20200031822-A1 CARBOLINE ANTIPARASITICS ZOETIS SERVICES LLC (US) 2020-01-30 US disclosed
EP-3313837-A1 CARBOLINE ANTIPARASITICS Zoetis Services LLC (US) 2018-05-02 EP disclosed
WO-2016209635-A1 CARBOLINE ANTIPARASITICS ZOETIS SERVICES LLC (US) 2016-12-29 WO disclosed
EP-1891042-B1 2-OXO-1-PYRROLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR THERAPEUTIC USE ON THE CENTRAL NERVOUS SYSTEM UCB PHARMA SA (BE) 2013-10-02 EP disclosed
US-8445731-B2 Process for producing bisphenol compound MITSUBISHI CHEMICAL CORPORATION (JP) 2013-05-21 US disclosed
EP-0944563-B1 SUBSTANCE MIXTURES CONTAINING STABILIZERS AND COMPOUNDS CONTAINING VINYL GROUPS BASF AG (DE) 2002-04-03 EP disclosed
US-6200460-B1 MIXTURE COMPRISING VINYL AROMATIC COMPOUND, ACTIVE AMOUNT OF MIXTURE WHICH INHIBITS THE PREMATURE POLYMERIZATION OF SAID COMPOUND COMPRISING NOXYL COMPOUND, IRON COMPOUND, OPTIONALLY NITRO COMPOUNDS AND COSTABILIZERS BASF AKTIENGESELLSCHAFT (DE) 2001-03-13 US disclosed
US-6143205-A A MIXTRUE COMPRISES A VINYL-CONTAINING MONOMERS, AND A MIXTURE OF PREMATURE POLYMERIZATION INHIBITOR OF MONOMERS DURING PURIFICATION OR DISTILLATION COMPRISING A N-OXYL COMPOUND OF SECONDARY AMINE AND A NITRO COMPOUND BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US disclosed
US-4972000-A MULTILAYER, CROSSLINKED PARTICLES FOR COATING COMPOSITIONS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-11-20 US disclosed
EP-0331421-A2 Hollow polymer particles, process for production thereof, and use thereof as pigment JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-09-06 EP disclosed
EP-0015385-B1 PROCESS FOR THE PREPARATION OF N-PROPYL- AND N-ETHYLCYANOACETIC ACID ESTERS HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1982-05-12 EP disclosed
EP-0015385-A1 Process for the preparation of n-propyl- and n-ethylcyanoacetic acid esters HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1980-09-17 EP disclosed
US-4212978-A Process for the catalytic production of 2-substituted pyridines LONZA LTD. (CH) 1980-07-15 US disclosed
US-4196287-A Process for the catalytic production of 2-substituted pyridines LONZA LTD. (CH) 1980-04-01 US disclosed
US-4141915-A REACTING AN UNSATURATED NITRILE, AN ALCOHOL, AND CARBON MONOXIDE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed