Styrene

Styrene

SCHEMBL8437178

C=Cc1ccccc1.CC=Cc1ccccn1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.52
RAB9A P51151 6/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
ATM Q13315 1/20 0.52
ALDH1A1 P00352 4/20 0.50
TSHR P16473 2/20 0.50
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
MAOA P21397 1/20 0.41
MAPT P10636 2/20 0.39
GRM4 Q14833 3/20 0.39
NR4A1 P22736 1/20 0.38
USP2 O75604 1/20 0.38
KDM4E B2RXH2 2/20 0.37
PKM P14618 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 1/20 0.37
GRM5 P41594 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8824964 0.88 NPC1 (0.50) NPC1RAB9AMEN1KMT2AATM
Styrene SCHEMBL607743 0.85 ALDH1A1 (0.58) NPC1RAB9AMEN1KMT2AATM
SCHEMBL455427 0.84
SCHEMBL178053 0.84
SCHEMBL93619 0.84
SCHEMBL30480966 0.84
Hydrochloric Acid SCHEMBL4201176 0.82 NPC1 (0.68) NPC1RAB9AMEN1KMT2AATM
Bromide SCHEMBL28229434 0.82 NPC1 (0.68) NPC1RAB9AMEN1KMT2AATM
Iodide SCHEMBL28203943 0.82 NPC1 (0.68) NPC1RAB9AMEN1KMT2AATM
Styrene SCHEMBL27506927 0.81 ALDH1A1 (0.54) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587182-B1 Process for producing compositions for ruminants KYOWA HAKKO KOGYO KK (JP) 1999-12-15 EP disclosed
US-5565212-A Process for producing compositions for ruminants KYOWA HAKKO KOGYO CO., LTD. (JP) 1996-10-15 US disclosed
EP-0587182-A2 Process for producing compositions for ruminants KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1994-03-16 EP disclosed