Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 4/20 | 0.33 |
| ▸ | JAK3 | P52333 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582626 | 0.86 | NPC1 (0.31) | — | |
| SCHEMBL1878389 | 0.86 | PDE4B (0.39) | PDE4B | |
| SCHEMBL12602578 | 0.85 | PTGER4 (0.34) | MELKJAK3JAK1JAK2LRRK2 | |
| SCHEMBL4500884 | 0.84 | ALDH1A1 (0.38) | — | |
| SCHEMBL6612611 | 0.83 | NPC1 (0.32) | — | |
| SCHEMBL4509685 | 0.83 | — | — | |
| SCHEMBL12602576 | 0.83 | — | — | |
| SCHEMBL4506957 | 0.83 | NPC1 (0.31) | PDE4B | |
| SCHEMBL12602531 | 0.82 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL12602565 | 0.82 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146966-B1 | 4-(3-AMINOBENZOYL)-1-METHYL PYRAZOLES AND THEIR APPLICATION AS HERBICIDES | BAYER IP GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-7943550-B2 | Controlling broadleaf plants, weeds, grasses | BAYER CROPSCIENCE AG (DE) | 2011-05-17 | — | — | US | disclosed |
| EP-2146966-A1 | 4-(3-AMINO BENZOYL)-1-METHYLPYRAZOLES AND THE USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008125213-A1 | 4-(3-AMINO BENZOYL)-1-METHYLPYRAZOLES AND THE USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| US-20080254992-A1 | 4-(3-Aminobenzoyl)-1 methylpyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| EP-1980553-A1 | 4-(3-aminobenzoyl)-1-methyl pyrazoles and their application as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2008-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080254992-A1 | 4-(3-Aminobenzoyl)-1 methylpyrazoles and their use as herbicides | TH, DDT, ABAT | PDE4B 1745/4885OPRM1 1584/4885MELK 894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.