Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 9/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15587106 | 0.77 | PTGER4 (0.34) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL21119072 | 0.77 | PTGER4 (0.34) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL18614168 | 0.73 | NOTUM (0.30) | — | |
| SCHEMBL18943211 | 0.73 | NOTUM (0.30) | — | |
| SCHEMBL16058266 | 0.71 | PTGER4 (0.64) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL16408738 | 0.69 | NPC1 (0.34) | PTGER4PTGER2 | |
| SCHEMBL15549241 | 0.67 | PTGER4 (0.64) | PTGER4PTGER2PTGER3 | |
| SCHEMBL17946216 | 0.63 | CHRM2 (0.38) | PTGER4PTGER2PTGER3 | |
| SCHEMBL11929362 | 0.63 | CHRM2 (0.38) | PTGER4PTGER2PTGER3 | |
| SCHEMBL12301043 | 0.63 | CHRM2 (0.38) | PTGER4PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160158413-A1 | METHODS, SYSTEMS, AND COMPOSITIONS FOR PROMOTING BONE GROWTH | CAYMAN CHEMICAL COMPANY, INC. (US) | 2016-06-09 | — | — | US | disclosed |