Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.30 |
| ▸ | MAPT | P10636 | 4/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15551554 | 0.82 | PTGER4 (0.44) | PTGER4PTGER2 | |
| SCHEMBL15551553 | 0.82 | PTGER4 (0.44) | PTGER4PTGER2 | |
| SCHEMBL16819439 | 0.81 | PTGER4 (0.44) | PTGER4PTGER2HPGDLMNAMAPK1 | |
| SCHEMBL22024693 | 0.81 | PTGER4 (0.44) | PTGER4PTGER2HPGDLMNAMAPK1 | |
| SCHEMBL16819436 | 0.81 | PTGER4 (0.44) | PTGER4PTGER2HPGDLMNAMAPK1 | |
| SCHEMBL15587052 | 0.81 | PTGER4 (0.44) | PTGER4PTGER2HPGDLMNAMAPK1 | |
| SCHEMBL18123907 | 0.78 | PTGER4 (0.35) | PTGER4PTGER2 | |
| SCHEMBL18123906 | 0.78 | PTGER4 (0.35) | PTGER4PTGER2 | |
| SCHEMBL18123909 | 0.78 | PTGER4 (0.35) | PTGER4PTGER2 | |
| SCHEMBL17808005 | 0.69 | PTGER4 (0.38) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015009991-A2 | METHODS, SYSTEMS, AND COMPOSITIONS FOR PROMOTING BONE GROWTH | CAYMAN CHEMICAL COMPANY, INC. (US) | 2015-01-22 | — | — | WO | disclosed |