SCHEMBL17809337

SCHEMBL17809337

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-n4c5ccccc5c5c6c7ccccc7n(-c7ccc(-c8cccc(-c9ccccc9)c8)cc7)c6ccc54)n3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NR3C1 P04150 1/20 0.35
HDAC4 P56524 1/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
RXRA P19793 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
LMNA P02545 2/20 0.33
RXFP1 Q9HBX9 1/20 0.33
GLA P06280 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18124934 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL23600345 0.99 KDM4E (0.38) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL26053730 0.99 KDM4E (0.38) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL26053624 0.99 KDM4E (0.38) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL20149419 0.99 KDM4E (0.38) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL23598384 0.97 KDM4E (0.39) KDM4EATML3MBTL1HDAC4MEN1
SCHEMBL23805722 0.97 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL21365518 0.97 L3MBTL1 (0.42) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL24549673 0.97 L3MBTL1 (0.42) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL19769806 0.96 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed