SCHEMBL17809368

SCHEMBL17809368

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5c4ccc4c6ccccc6n(-c6cccc7c6oc6ccccc67)c45)c3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.33
TSHR P16473 4/20 0.33
KDM4E B2RXH2 4/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 4/20 0.31
HSD17B10 Q99714 3/20 0.31
MAPK1 P28482 2/20 0.31
ALDH1A1 P00352 5/20 0.31
POLB P06746 2/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 3/20 0.31
MEN1 O00255 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
ALOX12 P18054 1/20 0.30
USP2 O75604 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24914624 0.92 KDM4E (0.35) TSHRKDM4EATML3MBTL1HSD17B10
SCHEMBL21365781 0.92 MAPT (0.34) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL17809143 0.92 MAPT (0.36) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL22192283 0.91 MAPT (0.33) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL22192635 0.91 MAPT (0.33) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL24914695 0.91 KDM4E (0.34) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL24357046 0.91 KDM4E (0.35) TSHRKDM4EATML3MBTL1LMNA
SCHEMBL17809148 0.90 MAPT (0.35) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL20988536 0.90 MAPT (0.35) MAPTTSHRKDM4ELMNAHSD17B10
SCHEMBL18124915 0.90 KDM4E (0.35) TSHRKDM4EATML3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed