SCHEMBL17809148

SCHEMBL17809148

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc(-n5c6ccccc6c6ccc7c8ccccc8n(-c8cccc9c8oc8ccccc89)c7c65)c4)n3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.35
TSHR P16473 5/20 0.35
ALOX5 P09917 1/20 0.33
KDM4E B2RXH2 4/20 0.33
LMNA P02545 4/20 0.33
HSD17B10 Q99714 3/20 0.33
MAPK1 P28482 2/20 0.33
ALDH1A1 P00352 5/20 0.33
POLB P06746 2/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALOX12 P18054 1/20 0.32
PRKDC P78527 1/20 0.32
USP2 O75604 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17809143 0.98 MAPT (0.36) MAPTTSHRALOX5KDM4ELMNA
SCHEMBL24217394 0.94 MAPT (0.36) MAPTTSHRALOX5KDM4ELMNA
SCHEMBL17809142 0.92 MAPT (0.34) MAPTTSHRALOX5KDM4ELMNA
SCHEMBL21740680 0.92 L3MBTL1 (0.36) MAPTTSHRALOX5KDM4EHSD17B10
SCHEMBL25133075 0.92 MAPT (0.36) MAPTTSHRALOX5KDM4ELMNA
SCHEMBL18505468 0.91 MAPT (0.37) MAPTTSHRALOX5KDM4ELMNA
SCHEMBL17990719 0.91 MAPT (0.37) MAPTTSHRALOX5KDM4ELMNA
SCHEMBL17809134 0.91 MAPT (0.37) MAPTTSHRALOX5KDM4ELMNA
SCHEMBL27442674 0.91 MAPT (0.34) MAPTTSHRALOX5KDM4ELMNA
SCHEMBL22192740 0.91 MAPT (0.35) MAPTTSHRALOX5KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed