Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PHGDH | O43175 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.55 |
| ▸ | APC | P25054 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309271 | 0.95 | HPGD (0.64) | HPGDALDH1A1MAPTLMNAPHGDH | |
| SCHEMBL14393702 | 0.83 | HPGD (0.61) | HPGDALDH1A1MAPTLMNAPHGDH | |
| SCHEMBL17194215 | 0.83 | HPGD (0.63) | HPGDALDH1A1MAPTSLC6A7LMNA | |
| SCHEMBL10720943 | 0.82 | PHGDH (0.81) | HPGDALDH1A1MAPTPHGDHSMN1; SMN2 | |
| SCHEMBL8739521 | 0.81 | HPGD (0.56) | HPGDALDH1A1MAPTLMNAHRH3 | |
| SCHEMBL8150805 | 0.81 | HPGD (0.76) | HPGDALDH1A1MAPTSLC6A7LMNA | |
| SCHEMBL16057730 | 0.81 | PHGDH (0.65) | HPGDALDH1A1MAPTLMNAPHGDH | |
| SCHEMBL2786906 | 0.81 | HPGD (0.73) | HPGDALDH1A1MAPTPHGDHHRH3 | |
| SCHEMBL10264405 | 0.80 | ALDH1A1 (0.62) | HPGDALDH1A1MAPTSLC6A7LMNA | |
| SCHEMBL300831 | 0.80 | HPGD (0.68) | HPGDALDH1A1MAPTSLC6A7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160158207-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158207-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | EP300, HDAC1, HDAC10 | HPGD 1938/4885ALDH1A1 1727/4885MAPT 3833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.