Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998877 | 0.71 | MCHR1 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL2815533 | 0.71 | MAPT (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL2817090 | 0.71 | CYP11B1 (0.53) | CYP11B1CYP11B2 | |
| Bromide SCHEMBL2818346 | 0.70 | MAPT (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL15110953 | 0.69 | KDM4C (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL22363049 | 0.68 | USP7 (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL17810139 | 0.68 | PDE10A (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL15111001 | 0.67 | APP (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL1500061 | 0.66 | MCHR1 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL16160303 | 0.66 | ALDH1A1 (0.36) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365540-B2 | Benzimidazole derivatives as MCH receptor antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-06-14 | — | — | US | disclosed |