Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233623 | 0.87 | HTT (0.56) | POLBHTTHPGDUSP2CASR | |
| SCHEMBL14362701 | 0.84 | POLB (0.43) | POLBHTTHPGDUSP2CASR | |
| SCHEMBL17810313 | 0.84 | POLB (0.49) | POLBHTTHPGDUSP2CASR | |
| SCHEMBL17810278 | 0.82 | POLB (0.47) | POLBHTTHPGDUSP2CASR | |
| SCHEMBL11231094 | 0.81 | HTT (0.66) | POLBHTTHPGDUSP2CASR | |
| SCHEMBL11340743 | 0.81 | USP2 (0.58) | HTTUSP2CASRHSD17B10CYP1A2 | |
| SCHEMBL23334641 | 0.79 | USP2 (0.61) | HTTUSP2CASRHSD17B10CYP1A2 | |
| SCHEMBL12441491 | 0.79 | USP2 (0.61) | HTTUSP2CASRHSD17B10CYP1A2 | |
| SCHEMBL20670848 | 0.79 | USP2 (0.61) | HTTUSP2CASRHSD17B10CYP1A2 | |
| SCHEMBL20670875 | 0.79 | USP2 (0.61) | HTTUSP2CASRHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160159660-A1 | SILICON CONTAINING POLYMER FLOCCULANTS | CYTEC INDUSTRIES INC. (US) | 2016-06-09 | — | — | US | disclosed |