Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24305909 | 0.85 | POLB (0.36) | POLBHTTHPGDKDM4EUSP2 | |
| SCHEMBL17810278 | 0.85 | POLB (0.47) | POLBHTTHPGDKDM4EUSP2 | |
| SCHEMBL17810294 | 0.84 | POLB (0.57) | POLBHTTHPGDKDM4EUSP2 | |
| SCHEMBL16298587 | 0.80 | USP2 (0.44) | HTTKDM4EUSP2HSD17B10CYP1A2 | |
| SCHEMBL17810285 | 0.80 | POLB (0.34) | POLBHTTHPGDCYP1A2CYP3A4 | |
| SCHEMBL20873145 | 0.79 | ADRB2 (0.34) | ADRB2ADRB1MEN1KMT2ACYP1A2 | |
| SCHEMBL9928007 | 0.78 | KDM4E (0.42) | HTTKDM4EUSP2HSD17B10ADRB2 | |
| SCHEMBL16298540 | 0.77 | KDM4E (0.44) | HTTKDM4EUSP2HSD17B10ADRB2 | |
| SCHEMBL15218995 | 0.76 | KDM4E (0.41) | POLBHTTKDM4EUSP2ADRB2 | |
| SCHEMBL14281336 | 0.75 | POLB (0.38) | POLBHTTHPGDKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160159660-A1 | SILICON CONTAINING POLYMER FLOCCULANTS | CYTEC INDUSTRIES INC. (US) | 2016-06-09 | — | — | US | disclosed |