SCHEMBL178107

SCHEMBL178107

CCCCCOP(=O)(OCl)OCCCCC

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.62
LPAR3 Q9UBY5 8/20 0.54
LPAR2 Q9HBW0 6/20 0.54
LPAR1 Q92633 3/20 0.54
TSHR P16473 1/20 0.48
LMNA P02545 1/20 0.43
ESR1 P03372 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
CDC25A P30304 1/20 0.43
AGTR1 P30556 1/20 0.43
AKT1 P31749 1/20 0.43
ADRA1A P35348 1/20 0.43
KCNH2 Q12809 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11350922 0.98 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL177972 0.98 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL7780302 0.98 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL28608720 0.98 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL1261050 0.98 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL5850379 0.98 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL177766 0.98 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL251881 0.95 CYP3A4 (0.62) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL25170777 0.93 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL7736725 0.93 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773417-B Cordycepin phosphate and preparation method and application thereof 郑州大学 2023-08-22 CN claimed
US-8350074-B2 Low triphenylphosphate, high phosphorous content isopropyl phenyl phosphates with high ortho alkylation ALBEMARLE CORPORATION (US) 2013-01-08 US claimed
US-20120004438-A1 Low Triphenylphosphate, High Phosphorous Content Isopropyl Phenyl Phosphates With High Ortho Alkylation ALBEMARLE CORPORATION (US) 2012-01-05 US claimed
US-20100012906-A1 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION ALBEMARLE CORPORATION (US) 2010-01-21 US claimed
JP-2009534469-A 2009-09-24 JP claimed
EP-2021347-A2 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION Albermarle Corporation (US) 2009-02-11 EP claimed
WO-2007127691-A2 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION ALBERMARLE CORPORATION (US) 2007-11-08 WO claimed
CN-116947924-A Camptothecin biphosphate compound and preparation method thereof 上海应用技术大学 2023-10-27 CN disclosed
CN-114773417-B Cordycepin phosphate and preparation method and application thereof 郑州大学 2023-08-22 CN disclosed
CN-114773417-A Cordycepin phosphate and preparation method and application thereof 郑州大学 2022-07-22 CN disclosed
EP-2389348-B1 PROCESS FOR THE SYNTHESIS OF BETA GLYCEROL PHOSPHATE SIGMA ALDRICH CO LLC (US) 2017-11-15 EP disclosed
US-20140179811-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS HICKORY SPRINGS MFG CO (US) 2014-06-26 US disclosed
US-8575225-B2 Use of low triphenylphosphate, high phosphorous content isopropyl phenyl phosphates as flame retardants in polyurethane or polyisocyanurate foams HICKORY SPRINGS MANUFACTURING COMPANY (US) 2013-11-05 US disclosed
WO-2008118695-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN RESINS ALBEMARLE CORPORATION (US) 2008-10-02 WO disclosed
US-20080092829-A1 FUEL COMPONENTS, FUEL COMPOSITIONS AND METHODS OF MAKING AND USING SAME AMYRIS BIOTECHNOLOGIES, INC. (US) 2008-04-24 US disclosed
WO-2007139925-A2 FUEL COMPONENTS, FUEL COMPOSITIONS AND METHODS OF MAKING AND USING SAME AMYRIS BIOTECHNOLOGIES, INC. (US) 2007-12-06 WO disclosed
WO-2007127691-A2 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION ALBERMARLE CORPORATION (US) 2007-11-08 WO disclosed
EP-1207182-B1 Flame retardant thermoplastic resin composition CHEIL IND INC (KR) 2004-04-07 EP disclosed
EP-1207182-A1 Flame retardant thermoplastic resin composition Cheil Industries Inc. (KR) 2002-05-22 EP disclosed
US-4851399-A Isoquinoline derivatives and their use as anti-cancer agents GLAXO GROUP LIMITED (GB) 1989-07-25 US disclosed