Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.57 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151411 | 1.00 | CYP3A4 (0.60) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL27873808 | 1.00 | CYP3A4 (0.60) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL6310977 | 1.00 | CYP3A4 (0.60) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL9328369 | 1.00 | CYP3A4 (0.60) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL1261033 | 1.00 | CYP3A4 (0.60) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL25170777 | 1.00 | CYP3A4 (0.60) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL251881 | 0.98 | CYP3A4 (0.62) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL28608720 | 0.96 | CYP3A4 (0.60) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL177766 | 0.96 | CYP3A4 (0.60) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL11350922 | 0.96 | CYP3A4 (0.60) | CYP3A4LPAR3LPAR2LPAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257996-A | PRESSING PARTICLES HAVING REACTIVE GROUPS | THE UPJOHN COMPANY (US) | 1981-03-24 | — | — | US | claimed |
| US-6413950-B1 | TOPICAL APPLICATION; SKIN DISORDERS | ESPARMA GMBH (DE) | 2002-07-02 | — | — | US | disclosed |
| US-5780504-A | Topical alkyl-2-O-L-ascorbyl-phosphates | AVON PRODUCTS, INC. (US) | 1998-07-14 | — | — | US | disclosed |
| US-5607968-A | Topical alkyl-2-O-L-ascorbyl-phosphates | AVON PRODUCTS, INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-4257996-A | PRESSING PARTICLES HAVING REACTIVE GROUPS | THE UPJOHN COMPANY (US) | 1981-03-24 | — | — | US | disclosed |