SCHEMBL178116

SCHEMBL178116

CC(O)C(OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.49
SLC1A2 P43004 2/20 0.49
SLC1A1 P43005 2/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
RCE1 Q9Y256 1/20 0.46
TSHR P16473 3/20 0.46
HTT P42858 3/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
MAPK1 P28482 1/20 0.46
MAPT P10636 1/20 0.44
CA1 P00915 3/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10720994 0.93 SLC1A3 (0.44) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL23723780 0.90 RCE1 (0.50) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL10718173 0.87 PPARG (0.43) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL10719263 0.87 CETP (0.47) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL9662131 0.85 CETP (0.49) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL7155541 0.85 MAPT (0.53) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL17663535 0.85 MAPT (0.53) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL10717717 0.84 CETP (0.51) KMT2AMEN1CYP2C9CYP2C19TSHR
SCHEMBL10717605 0.84 CETP (0.51) KMT2AMEN1CYP2C9CYP2C19TSHR
SCHEMBL10717589 0.84 CETP (0.51) KMT2AMEN1CYP2C9CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111961077-B Preparation method of beta sodium glycerophosphate containing crystal water 山西千岫制药有限公司 2023-06-20 CN disclosed
CN-111961077-A Preparation method of beta sodium glycerophosphate containing crystal water 山西千岫制药有限公司 2020-11-20 CN disclosed
EP-3353183-A1 N-[2-(2-AMINO-6,6-DISUBSTITUTED-4, 4A, 5, 6-TETRAHYDROPYRANO [3,4-D][1,3]THIAZIN-8A (8H)-YL) -1, 3-THIAZOL-4-YL]AMIDES Pfizer Inc (US) 2018-08-01 EP disclosed
CN-108135188-A For the precursor compound of molecular coatings 阿比尔技术公司 2018-06-08 CN disclosed
WO-2017051276-A1 N-[2-(2-AMINO-6,6-DISUBSTITUTED-4, 4A, 5, 6-TETRAHYDROPYRANO [3,4-D][1,3] THIAZIN-8A (8H)-YL) -1, 3-THIAZOL-4-YL] AMIDES PFIZER INC. (US) 2017-03-30 WO disclosed
EP-3083604-A1 UREA DERIVATIVES USEFUL AS KINASE INHIBITORS Respivert Limited (GB) 2016-10-26 EP disclosed
EP-3007727-A1 POLYDENDRONS The University of Liverpool (GB) 2016-04-20 EP disclosed
EP-2931838-A1 LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2015-10-21 EP disclosed
WO-2015092423-A1 UREA DERIVATIVES USEFUL AS KINASE INHIBITORS RESPIVERT LIMITED (GB) 2015-06-25 WO disclosed
WO-2014199174-A1 POLYDENDRONS THE UNIVERSITY OF LIVERPOOL (GB) 2014-12-18 WO disclosed
EP-1870409-A1 BENZIMIDAZOLE COMPOUND Eisai R&D Management Co., Ltd. (JP) 2007-12-26 EP disclosed
WO-2007144327-A2 PHENYL-PYRAZOLE DERIVATIVES AS NON-STEROIDAL GLUCOCORICOID RECEPTOR LIGANDS GLAXO GROUP LIMITED (GB) 2007-12-21 WO disclosed
WO-2007140483-A2 FILMS AND PARTICLES THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2007-12-06 WO disclosed
US-20070015782-A1 Benzimidazole compound EISAI CO., LTD. 2007-01-18 US disclosed
EP-1181017-A1 METALLOPROTEASE INHIBITORS Pfizer Limited (GB) 2002-02-27 EP disclosed
EP-1061954-A1 POLY(ETHYLENE GLYCOL) DERIVATIVES WITH PROXIMAL REACTIVE GROUPS Shearwater Polymers, Incorporated (US) 2000-12-27 EP disclosed
WO-2000074681-A1 METALLOPROTEASE INHIBITORS PFIZER LIMITED (GB) 2000-12-14 WO disclosed
EP-0988304-A1 NUCLEOSIDES ANALOGUES, SUCH AS ANTIVIRALS INCLUDING INHIBITORS OF RETROVIRAL REVERSE TRANSCRIPTASE AND THE DNA POLYMERASE OF HEPATITIS B VIRUS (HBV) MEDIVIR AB (SE) 2000-03-29 EP disclosed
WO-1999045964-A1 POLY(ETHYLENE GLYCOL) DERIVATIVES WITH PROXIMAL REACTIVE GROUPS SHEARWATER POLYMERS, INCORPORATED (US) 1999-09-16 WO disclosed
WO-1999009031-A1 NUCLEOSIDES ANALOGUES, SUCH AS ANTIVIRALS INCLUDING INHIBITORS OF RETROVIRAL REVERSE TRANSCRIPTASE AND THE DNA POLYMERASE OF HEPATITIS B VIRUS (HBV) MEDIVIR AB (SE) 1999-02-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070015782-A1 Benzimidazole compound HRH2, GIPR, HRH4 SLC1A3 1469/4885SLC1A2 3805/4885SLC1A1 2118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.