⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17388557 | 0.91 | — | — | |
| SCHEMBL1445018 | 0.87 | — | — | |
| SCHEMBL1928749 | 0.87 | CYP1A2 (0.36) | — | |
| SCHEMBL12654754 | 0.86 | HTT (0.30) | — | |
| SCHEMBL7908323 | 0.86 | — | — | |
| SCHEMBL22672397 | 0.84 | CYP1A2 (0.40) | — | |
| SCHEMBL462050 | 0.84 | CYP1A2 (0.40) | — | |
| SCHEMBL10468230 | 0.82 | ALDH1A1 (0.38) | — | |
| SCHEMBL9313545 | 0.80 | — | — | |
| SCHEMBL9315025 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150327-A1 | BIPYRAZOLE DERIVATIVES AS JAK INHIBITORS | INCYTE CORPORATION | 2024-05-09 | — | — | US | claimed |
| US-11905275-B2 | Bipyrazole derivatives as JAK inhibitors | INCYTE CORPORATION (US) | 2024-02-20 | — | — | US | claimed |
| EP-4275756-A2 | BIPYRAZOLE DERIVATIVES AS JAK INHIBITORS | Incyte Holdings Corporation (US) | 2023-11-15 | — | — | EP | claimed |
| EP-3786162-B1 | BIPYRAZOLE DERIVATIVES AS JAK INHIBITORS | INCYTE HOLDINGS CORP (US) | 2023-08-09 | — | — | EP | claimed |
| EP-3743430-B1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-02 | — | — | EP | claimed |
| US-20230159501-A1 | BIPYRAZOLE DERIVATIVES AS JAK INHIBITORS | INCYTE CORPORATION | 2023-05-25 | — | — | US | claimed |
| US-11591318-B2 | Bipyrazole derivatives as JAK inhibitors | INCYTE CORPORATION (US) | 2023-02-28 | — | — | US | claimed |
| CN-113717170-A | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2021-11-30 | — | — | CN | claimed |
| US-20210330651-A1 | ESTROGEN RECEPTOR MODULATORS | RECURIUM IP HOLDINGS, LLC | 2021-10-28 | — | — | US | claimed |
| US-20210238168-A1 | BIPYRAZOLE DERIVATIVES AS JAK INHIBITORS | INCYTE CORPORATION | 2021-08-05 | — | — | US | claimed |
| EP-2721028-A1 | AZETIDINYL PHENYL, PYRIDYL OR PYRAZINYL CARBOXAMIDE DERIVATIVES AS JAK INHIBITORS | Incyte Corporation (US) | 2014-04-23 | — | — | EP | claimed |
| US-20140051626-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2014-02-20 | — | — | US | claimed |
| US-8513186-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2013-08-20 | — | — | US | claimed |
| WO-2012177606-A1 | AZETIDINYL PHENYL, PYRIDYL OR PYRAZINYL CARBOXAMIDE DERIVATIVES AS JAK INHIBITORS | INCYTE CORPORATION (US) | 2012-12-27 | — | — | WO | claimed |
| CN-102134194-A | Ester compound with insecticidal activity | JIANGSU YANGNONG CHEMICAL CO | 2011-07-27 | — | — | CN | claimed |
| EP-2200612-A1 | INHIBITORS OF JANUS KINASES | Merck Sharp & Dohme Corp. (US) | 2010-06-30 | — | — | EP | claimed |
| EP-2162432-A2 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2010-03-17 | — | — | EP | claimed |
| US-20090186869-A1 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2009-07-23 | — | — | US | claimed |
| WO-2009035575-A1 | INHIBITORS OF JANUS KINASES | MERCK & CO., INC. (US) | 2009-03-19 | — | — | WO | claimed |
| WO-2009005677-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | claimed |