Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17807593 | 0.92 | MDM2 (0.45) | MDM2TLR2PTPN1EPHX2SIRT1 | |
| SCHEMBL17813684 | 0.89 | TLR2 (0.45) | MDM2TLR2PTPN1SIRT1 | |
| SCHEMBL26015705 | 0.89 | TLR2 (0.46) | MDM2TLR2SIRT1 | |
| SCHEMBL22690495 | 0.84 | CASP3 (0.45) | TLR2PTPN1SIRT1 | |
| SCHEMBL19302505 | 0.84 | CASP3 (0.45) | TLR2PTPN1SIRT1 | |
| SCHEMBL29423466 | 0.84 | CASP3 (0.45) | TLR2PTPN1SIRT1 | |
| SCHEMBL2734926 | 0.83 | PTPN1 (0.47) | PTPN1SIRT1 | |
| SCHEMBL12972289 | 0.83 | PTPN1 (0.47) | PTPN1SIRT1 | |
| SCHEMBL26015651 | 0.83 | TLR2 (0.44) | MDM2TLR2SIRT1 | |
| SCHEMBL26015589 | 0.81 | MDM2 (0.46) | MDM2TLR2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016090050-A1 | QUATERNARY AMINE COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2016-06-09 | — | — | WO | disclosed |