Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.33 |
| ▸ | CCNC | P24863 | 2/20 | 0.32 |
| ▸ | CDK8 | P49336 | 2/20 | 0.32 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.31 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17814095 | 0.83 | CYP11B1 (0.45) | CYP11B1CYP11B2 | |
| SCHEMBL19348316 | 0.83 | CCNC (0.35) | PAK1CYP11B1CYP11B2CCNCCDK8 | |
| SCHEMBL17814087 | 0.83 | CYP11B2 (0.51) | CYP11B1CYP11B2 | |
| SCHEMBL21105117 | 0.82 | CYP11B2 (0.35) | PAK1CYP11B1CYP11B2CCNCCDK8 | |
| SCHEMBL17814094 | 0.82 | CYP11B1 (0.36) | PAK1CYP11B1CYP11B2CCNCCDK8 | |
| SCHEMBL17814129 | 0.74 | CYP11B2 (0.46) | CYP11B1CYP11B2PRMT5WDR77 | |
| SCHEMBL17814134 | 0.72 | CYP11B2 (0.50) | CYP11B1CYP11B2 | |
| SCHEMBL21105221 | 0.72 | PRMT5 (0.34) | PAK1CYP11B1CYP11B2PRMT5WDR77 | |
| SCHEMBL19348314 | 0.70 | PRMT5 (0.37) | PAK1CYP11B1CYP11B2CCNCCDK8 | |
| SCHEMBL17814210 | 0.69 | CYP11B1 (0.36) | PAK1CYP11B1CYP11B2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089800-A1 | ALDOSTERONE SYNTHASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-06-09 | — | — | WO | disclosed |