SCHEMBL17814271

SCHEMBL17814271

N#C/C(NCc1ccccc1)=C(\C#N)NCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.61
ALOX12 P18054 3/20 0.54
HPGD P15428 2/20 0.54
ALDH1A1 P00352 2/20 0.54
GAA P10253 4/20 0.52
MAPT P10636 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
POLB P06746 1/20 0.52
LMNA P02545 2/20 0.51
PLIN1 O60240 1/20 0.51
PLIN5 Q00G26 1/20 0.51
ABHD5 Q8WTS1 1/20 0.51
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
THRB P10828 1/20 0.48
IDO1 P14902 1/20 0.48
HDAC2 Q92769 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17763698 1.00 MCL1 (0.61) MCL1ALOX12HPGDALDH1A1GAA
SCHEMBL17763697 1.00 MCL1 (0.61) MCL1ALOX12HPGDALDH1A1GAA
SCHEMBL6729091 0.87 MCL1 (0.53) MCL1ALOX12HPGDALDH1A1GAA
SCHEMBL11498666 0.87 MCL1 (0.53) MCL1ALOX12HPGDALDH1A1GAA
SCHEMBL6729087 0.87 MCL1 (0.53) MCL1ALOX12HPGDALDH1A1GAA
SCHEMBL653442 0.79 MCL1 (0.62) MCL1ALOX12HPGDALDH1A1GAA
SCHEMBL17763699 0.79 LMNA (0.49) MCL1ALOX12HPGDALDH1A1GAA
SCHEMBL17814240 0.79 LMNA (0.49) MCL1ALOX12HPGDALDH1A1GAA
SCHEMBL17763700 0.79 LMNA (0.49) MCL1ALOX12HPGDALDH1A1GAA
SCHEMBL22306421 0.76 HPGD (0.51) MCL1ALOX12HPGDALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9722280-B2 Acrylonitrile derivatives as additive for electrolytes in lithium ion batteries BASF SE (DE) 2017-08-01 US disclosed
US-20160164141-A1 ACRYLONITRILE DERIVATIVES AS ADDITIVE FOR ELECTROLYTES IN LITHIUM ION BATTERIES BASF SE (DE) 2016-06-09 US disclosed