Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898045 | 0.94 | HSP90AA1 (0.58) | HSP90AA1GSK3AGSK3BTRPV1MGLL | |
| SCHEMBL17898046 | 0.83 | SMN1; SMN2 (0.49) | HSP90AA1TRPV1PTGS1CCR5ALDH1A1 | |
| SCHEMBL178977 | 0.81 | TRPV1 (0.57) | TRPV1PTGS1CCR5ALDH1A1KDM4E | |
| SCHEMBL6941838 | 0.81 | GSK3A (0.67) | HSP90AA1GSK3AGSK3BMGLLPTGS2 | |
| SCHEMBL17889166 | 0.80 | TRPV1 (0.52) | HSP90AA1TRPV1PTGS1PTGS2CCR5 | |
| SCHEMBL14678150 | 0.79 | HSP90AA1 (1.00) | HSP90AA1GSK3AGSK3BALDH1A1HTT | |
| SCHEMBL178978 | 0.78 | TRPV1 (0.58) | TRPV1PTGS1CCR5ALDH1A1KDM4E | |
| SCHEMBL17253827 | 0.77 | CYP4F2 (0.54) | TRPV1PTGS1PTGS2CCR5ALDH1A1 | |
| SCHEMBL9588895 | 0.77 | TRPV1 (0.60) | TRPV1PTGS1CCR5ALDH1A1KDM4E | |
| SCHEMBL10483834 | 0.75 | KDM4E (0.56) | TRPV1PTGS1CCR5ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540462-B2 | Catechol-rich polymers from N-substituted maleimides | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-01-10 | — | — | US | disclosed |
| US-9540462-B2 | Catechol-rich polymers from N-substituted maleimides | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-01-10 | — | — | US | disclosed |
| US-20160194415-A1 | CATECHOL-RICH POLYMERS FROM N-SUBSTITUTED MALEIMIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2016-07-07 | — | — | US | disclosed |
| US-20160194415-A1 | CATECHOL-RICH POLYMERS FROM N-SUBSTITUTED MALEIMIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2016-07-07 | — | — | US | disclosed |
| WO-2016090355-A2 | CATECHOL-RICH POLYMERS FROM N-SUBSTITUTED MALEIMIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194415-A1 | CATECHOL-RICH POLYMERS FROM N-SUBSTITUTED MALEIMIDES | VIM, COMT, PNMT | HSP90AA1 1236/4885GSK3A 3276/4885GSK3B 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.