Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240031 | 0.91 | HTT (0.36) | HTTMEN1KMT2AACHEPOLB | |
| SCHEMBL2240036 | 0.91 | HTT (0.36) | HTTMEN1KMT2AACHEPOLB | |
| SCHEMBL178182 | 0.90 | KCNH2 (0.36) | MEN1KMT2AACHEPOLBTSHR | |
| SCHEMBL176925 | 0.84 | HTT (0.40) | HTTMEN1KMT2A | |
| SCHEMBL176926 | 0.84 | HTT (0.40) | HTTMEN1KMT2A | |
| SCHEMBL178080 | 0.81 | KCNH2 (0.33) | MEN1KMT2AACHEPOLBTSHR | |
| SCHEMBL2240042 | 0.81 | KCNH2 (0.33) | MEN1KMT2AACHEPOLBTSHR | |
| SCHEMBL177214 | 0.80 | TRPV1 (0.31) | — | |
| SCHEMBL176707 | 0.79 | GRM2 (0.41) | MEN1KMT2AACHEPOLBTSHR | |
| SCHEMBL176708 | 0.79 | GRM2 (0.41) | MEN1KMT2AACHEPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |