Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178080 | 0.91 | KCNH2 (0.33) | KCNH2ACHEPOLBTSHRHSD17B10 | |
| SCHEMBL2240042 | 0.91 | KCNH2 (0.33) | KCNH2ACHEPOLBTSHRHSD17B10 | |
| SCHEMBL178153 | 0.90 | HTT (0.40) | ACHEPOLBTSHRHSD17B10ALDH1A1 | |
| Toluene SCHEMBL2239924 | 0.88 | KCNH2 (0.32) | KCNH2ACHEPOLBTSHRHSD17B10 | |
| SCHEMBL177159 | 0.84 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL2240031 | 0.81 | HTT (0.36) | ACHEPOLBTSHRHSD17B10ALDH1A1 | |
| SCHEMBL2240036 | 0.81 | HTT (0.36) | ACHEPOLBTSHRHSD17B10ALDH1A1 | |
| SCHEMBL176707 | 0.79 | GRM2 (0.41) | ACHEPOLBTSHRHSD17B10ALDH1A1 | |
| SCHEMBL176708 | 0.79 | GRM2 (0.41) | ACHEPOLBTSHRHSD17B10ALDH1A1 | |
| SCHEMBL176926 | 0.77 | HTT (0.40) | KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |