Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17816335 | 0.98 | ESR1 (0.35) | ESR1ESR2MAPT | |
| SCHEMBL17816334 | 0.92 | ESR1 (0.32) | ESR1ESR2MAPT | |
| SCHEMBL17816333 | 0.90 | ESR1 (0.31) | ESR1ESR2 | |
| SCHEMBL17816336 | 0.90 | ESR1 (0.31) | ESR1ESR2 | |
| SCHEMBL17816507 | 0.88 | ESR1 (0.34) | ESR1ESR2MAPT | |
| SCHEMBL19755897 | 0.88 | HDAC3 (0.33) | ESR1ESR2MAPT | |
| SCHEMBL17816339 | 0.87 | — | — | |
| SCHEMBL19755899 | 0.86 | — | — | |
| SCHEMBL8464699 | 0.86 | ESR1 (0.31) | ESR1ESR2 | |
| SCHEMBL19741586 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422315-B2 | Organosiloxane composition having high refractive index and applications containing the same | MOMENTIVE PERFORMANCE MATERIALS JAPAN LLC (JP) | 2016-08-23 | — | — | US | disclosed |
| US-9422315-B2 | Organosiloxane composition having high refractive index and applications containing the same | MOMENTIVE PERFORMANCE MATERIALS JAPAN LLC (JP) | 2016-08-23 | — | — | US | disclosed |
| US-20160159829-A1 | ORGANOSILOXANE COMPOSITION HAVING HIGH REFRACTIVE INDEX AND APPLICATIONS CONTAINING THE SAME | MOMENTIVE PERFORMANCE MATERIALS JAPAN LLC (JP) | 2016-06-09 | — | — | US | disclosed |
| US-20160159829-A1 | ORGANOSILOXANE COMPOSITION HAVING HIGH REFRACTIVE INDEX AND APPLICATIONS CONTAINING THE SAME | MOMENTIVE PERFORMANCE MATERIALS JAPAN LLC (JP) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159829-A1 | ORGANOSILOXANE COMPOSITION HAVING HIGH REFRACTIVE INDEX AND APPLICATIONS CONTAINING THE SAME | XPA, SQLE, F12 | ESR1 2740/4885ESR2 3972/4885MAPT 3814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.