SCHEMBL8464699

SCHEMBL8464699

[CH2]CC[Si](C)(C)O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17816335 0.88 ESR1 (0.35) ESR1ESR2
SCHEMBL17816338 0.86 ESR1 (0.34) ESR1ESR2
SCHEMBL19755897 0.82 HDAC3 (0.33) ESR1ESR2
SCHEMBL17816334 0.82 ESR1 (0.32) ESR1ESR2
SCHEMBL17816333 0.81 ESR1 (0.31) ESR1ESR2
SCHEMBL17816336 0.81 ESR1 (0.31) ESR1ESR2
SCHEMBL17816507 0.79 ESR1 (0.34) ESR1ESR2
SCHEMBL15949966 0.78
SCHEMBL15949873 0.78
SCHEMBL17816339 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4933406-A OXYGEN-PERMEABLE, RIGID NIPPON OIL AND FATS CO., LTD. (JP) 1990-06-12 US claimed
US-5883152-A HARD CONTACT LENS CONSISTING OF A COPOLYMER OF CARBOXYLIC ACID ESTER MONOMER, TRIS(TRIMETHYLSILOXY)SILYLPROPYL(METH)ACRYLATE, AND COPOLYMERIZABLE MONOMER NIPPON OIL AND FATS CO., LTD. (JP) 1999-03-16 US disclosed
EP-0425831-B1 Contact lens NIPPON OILS & FATS CO LTD (JP) 1995-05-03 EP disclosed
EP-0425831-A2 Contact lens NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-05-08 EP disclosed
US-4933406-A OXYGEN-PERMEABLE, RIGID NIPPON OIL AND FATS CO., LTD. (JP) 1990-06-12 US disclosed