Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781152 | 0.81 | — | — | |
| SCHEMBL1241800 | 0.79 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL16458892 | 0.79 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL6672019 | 0.79 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL4519561 | 0.79 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL8762300 | 0.78 | — | — | |
| SCHEMBL29381599 | 0.77 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL6673537 | 0.77 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL30890195 | 0.77 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL31135174 | 0.77 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300670-A | Fluorosilicone polymer and curable fluorosilicone polymer composition | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1994-04-05 | — | — | US | claimed |
| EP-0567970-A1 | Fluorosilicone polymer and curable fluorosilicone polymer composition | Dow Corning Toray Silicone Company, Limited (JP) | 1993-11-03 | — | — | EP | claimed |
| EP-4073078-A1 | PROCESSES FOR SYNTHESIZING UNSYMMETRICAL DISILOXANES | Dow Silicones Corporation (US) | 2022-10-19 | — | — | EP | disclosed |
| US-8263709-B2 | Crystal nucleating agents, crystalline polymer composition, methods of manufacture thereof, and articles thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2012-09-11 | — | — | US | disclosed |
| US-20110118415-A1 | CRYSTAL NUCLEATING AGENTS, CRYSTALLINE POLYMER COMPOSITION, METHODS OF MANUFACTURE THEREOF, AND ARTICLES THEREOF | THE UNIVERSITY OF MASSACHUSETTS (US) | 2011-05-19 | — | — | US | disclosed |
| EP-0739384-B1 | LOW COEFFICIENT OF FRICTION SILICONE RELEASE FORMULATIONS INCORPORATING HIGHER ALKENYL-FUNCTIONAL SILICONE GUMS | MINNESOTA MINING & MFG (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0586216-B1 | Organosiloxane compositions exhibiting improved bonding to substrates during curing | DOW CORNING (US) | 1997-06-04 | — | — | EP | disclosed |
| EP-0739384-A1 | LOW COEFFICIENT OF FRICTION SILICONE RELEASE FORMULATIONS INCORPORATING HIGHER ALKENYL-FUNCTIONAL SILICONE GUMS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-10-30 | — | — | EP | disclosed |
| US-5520978-A | THIN FLEXIBLE SUBSTRATE HAVING CURED COATINGS OF ETHENICALLY UNSATURATED POLYSILOXANE, A HYDRIDOPOLYSILOXANE CROSSLINKING AGENT, A PLATINUM OR RHODIUM CATALYST AND A POLYSILOXANE GUM HAVING UNSATURATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-28 | — | — | US | disclosed |
| US-5468815-A | Curable coating | MINNESOTA MINING AND MANUFACTURING (US) | 1995-11-21 | — | — | US | disclosed |
| WO-1995019394-A1 | LOW COEFFICIENT OF FRICTION SILICONE RELEASE FORMULATIONS INCORPORATING HIGHER ALKENYL-FUNCTIONAL SILICONE GUMS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-07-20 | — | — | WO | disclosed |
| US-5386007-A | Siloxane copolymers containing alkenyl groups, their preparation and their use | WACKER-CHEMIE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |
| EP-0361477-B1 | Method for manufacturing an alkenyl group-containing organopolysiloxane | TORAY SILICONE CO (JP) | 1994-07-27 | — | — | EP | disclosed |
| EP-0586216-A2 | Organosiloxane compositions exhibiting improved bonding to substrates during curing | DOW CORNING CORPORATION (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5283307-A | Curable composition of unsaturated polysiloxane, polyhydrogen siloxane curing agent, platinum containing hydrosilation catalyst, adhesion promoting unsaturated silane compound with at least one alkoxy group | DOW CORNING CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| US-4980439-A | Method for manufacturing an alkenyl group-containing organopolysiloxane | TORAY SILICONE COMPANY LIMITED (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0361477-A2 | Method for manufacturing an alkenyl group-containing organopolysiloxane | TORAY SILICONE COMPANY, LIMITED (JP) | 1990-04-04 | — | — | EP | disclosed |