SCHEMBL6673537

SCHEMBL6673537

C=CCCCCCCCC[Si](C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 4/20 0.43
ABCC4 O15439 1/20 0.39
MAPT P10636 1/20 0.39
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 2/20 0.38
TRPA1 O75762 2/20 0.37
USP2 O75604 1/20 0.35
HPGD P15428 1/20 0.35
LPAR3 Q9UBY5 2/20 0.34
LPAR2 Q9HBW0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384354 1.00 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL31135174 1.00 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL8785965 1.00 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL29383760 1.00 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL3676407 1.00 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL29381599 1.00 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL29381466 1.00 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL6672019 0.97 TSHR (0.48) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL3673730 0.89
SCHEMBL29236617 0.84 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118530395-A Ethylene/alpha-olefin copolymer and process for producing the same 中国科学院化学研究所 2024-08-23 CN claimed
US-20240209198-A1 OLEFIN-BASED POLYMER COMPOSITIONS WITH IMPROVED CURE DOW GLOBAL TECHNOLOGIES LLC (US) 2024-06-27 US disclosed
US-20230272206-A1 CROSSLINKABLE OLEFIN/SILANE INTERPOLYMER COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-08-31 US disclosed
WO-2022078046-A1 POLYMER HAVING DISPERSING FUNCTION, POLYCARBOXYLIC ACID CEMENT DISPERSANT, PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2022-04-21 WO disclosed
WO-2022033588-A1 POLYMER HAVING DISPERSING FUNCTION, OIL WELL CEMENT DISPERSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2022-02-17 WO disclosed
CN-108276412-B Glycolurils having glycidyl group and use thereof 四国化成工业株式会社 2021-02-02 CN disclosed
EP-3369735-A1 GLYCOLURILS HAVING FUNCTIONAL GROUP AND USE THEREOF Shikoku Chemicals Corporation (JP) 2018-09-05 EP disclosed
US-10000622-B2 Glycolurils having functional groups and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2018-06-19 US disclosed
US-9562119-B2 Ethylene polymerization catalysts W. R. GRACE & CO.-CONN. (US) 2017-02-07 US disclosed
US-20160297951-A1 GLYCOLURILS HAVING FUNCTIONAL GROUPS AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2016-10-13 US disclosed
EP-0744415-A1 Solid titanium catalyst component, ethylene polymerization catalyst containing the same, and ethylene polymerization process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-11-27 EP disclosed
EP-0534119-B1 Prepolymerized olefin polymerization catalyst and olefin polymerization process MITSUI PETROCHEMICAL IND (JP) 1996-01-31 EP disclosed
US-5478890-A Molding materials MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-12-26 US disclosed
US-5476903-A Composition containing copolymer of alpha-olefin and polyene with another polyolefin polymerized in presence of prepolymerized catalyst containing said copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-12-19 US disclosed
EP-0683175-A2 Solid titanium catalyst component for olefin polymerization, process for preparation of the same, olefin polymerization catalyst and process for olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-11-22 EP disclosed
EP-0679661-A1 Prepolymerized olefin polymerization catalyst and polymerization process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-11-02 EP disclosed
US-5438100-A Olefin polymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-08-01 US disclosed
EP-0611780-A2 Polyolefin containing an alpha-olefin/polyene copolymer and products comprising this polyolefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-08-24 EP disclosed
EP-0536503-A2 Olefin polymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-04-14 EP disclosed
EP-0534119-A2 Prepolymerized olefin polymerization catalyst and olefin polymerization process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160297951-A1 GLYCOLURILS HAVING FUNCTIONAL GROUPS AND USE THEREOF ELOVL5, DEGS1, ACSL5 TSHR 2777/4885ALDH1A1 1884/4885ABCC4 1368/4885
US-10000622-B2 Glycolurils having functional groups and use thereof ELOVL5, DEGS1, ACSL5 TSHR 2777/4885ALDH1A1 1884/4885ABCC4 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.