Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797480 | 1.00 | LIMK1 (0.50) | LIMK1IRAK4TSHRCCNA2CDK2 | |
| SCHEMBL15933927 | 0.84 | LIMK1 (0.50) | LIMK1IRAK4TSHRCSNK2A2CSNK2B | |
| SCHEMBL15923690 | 0.84 | LIMK1 (0.50) | LIMK1IRAK4TSHRCSNK2A2CSNK2B | |
| SCHEMBL15923688 | 0.84 | LIMK1 (0.50) | LIMK1IRAK4TSHRCSNK2A2CSNK2B | |
| SCHEMBL14459722 | 0.83 | LIMK1 (0.70) | LIMK1TSHRCCNA2CDK2CCNA1 | |
| SCHEMBL17850662 | 0.83 | LIMK1 (0.70) | LIMK1TSHRCCNA2CDK2CCNA1 | |
| SCHEMBL16741730 | 0.80 | MKNK1 (0.62) | LIMK1MKNK1 | |
| SCHEMBL15534282 | 0.79 | MKNK1 (0.56) | LIMK1LMNAALDH1A1MKNK1 | |
| SCHEMBL16384777 | 0.79 | MKNK1 (0.56) | LIMK1LMNAALDH1A1MKNK1 | |
| SCHEMBL16372092 | 0.79 | MKNK1 (0.56) | LIMK1LMNAALDH1A1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160159816-A1 | SUBSTITUTED THIENOPYRIMIDINES AND PHARMACEUTICAL USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159816-A1 | SUBSTITUTED THIENOPYRIMIDINES AND PHARMACEUTICAL USE THEREOF | TYMP, DPYD, TYMS | LIMK1 3605/4885IRAK4 3975/4885TSHR 3295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.