⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19123729 | 1.00 | — | — | |
| SCHEMBL21577152 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28051922 | 0.98 | — | — | |
| SCHEMBL347526 | 0.86 | — | — | |
| SCHEMBL13354141 | 0.86 | — | — | |
| SCHEMBL11997889 | 0.86 | — | — | |
| SCHEMBL1307154 | 0.85 | — | — | |
| SCHEMBL14084413 | 0.85 | ADH1B (0.60) | — | |
| Hydrochloric Acid SCHEMBL28291319 | 0.83 | ADH1B (0.62) | — | |
| Hydrogen Peroxide SCHEMBL28104200 | 0.83 | ADH1B (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325509-A | Functional derivative compound of alanine and proline amino acid and pharmaceutical composition containing same | 阿米蒂比奥有限公司 | 2019-10-11 | — | — | CN | claimed |
| CN-110036006-A | The preparation and use of pyrimidone derivatives | 癌症研究科技有限公司 | 2019-07-19 | — | — | CN | claimed |
| CN-109310668-A | Positive allosteric modulators of muscarinic acetylcholine receptor M4 | 范德比尔特大学 | 2019-02-05 | — | — | CN | claimed |
| CN-109311880-A | For treating and preventing hepatitis b virus infected new tetrahydropyridine miazines compound | 豪夫迈·罗氏有限公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109311819-A | Isoquinolin -3- base benzamide type and its preparation and its purposes | 萨穆梅德有限公司 | 2019-02-05 | — | — | CN | claimed |
| CN-108699035-A | Noval chemical compound | 特殊治疗有限公司 | 2018-10-23 | — | — | CN | claimed |
| CN-105793251-B | Heteroaryl pyridines ketone with electrophilic functionality and azepine-pyridinone compounds | 豪夫迈·罗氏有限公司 | 2018-10-12 | — | — | CN | claimed |
| CN-108290872-A | Cyanopyrolidine derivatives as DUBs inhibitor | 特殊治疗有限公司 | 2018-07-17 | — | — | CN | claimed |
| CN-107849044-A | Thriazaspiro last of the ten Heavenly stems ketone compounds as DDR1 inhibitor | 豪夫迈·罗氏有限公司 | 2018-03-27 | — | — | CN | claimed |
| CN-107759587-A | [1,2,4] triazol [1,5 a] pyridine compounds and their and preparation method thereof and medical usage | 中国医药研究开发中心有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-103442568-A | Furo [3,2-d ] pyrimidine compounds | ABBVIE INC | 2013-12-11 | — | — | CN | claimed |
| EP-2215085-B1 | PYRIDINE AND PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2011-09-07 | — | — | EP | claimed |
| US-20110118238-A1 | 2-ANILINOPURIN-8-ONES AS INHIBITORS OF TTK/MPS1 FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2011-05-19 | — | — | US | claimed |
| EP-2215085-A2 | PYRIDINE AND PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | AstraZeneca AB (SE) | 2010-08-11 | — | — | EP | claimed |
| EP-2212326-A1 | 2-ANILINOPURIN-8-ONES AS INHIBITORS OF TTK/MPS1 FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AstraZeneca AB (SE) | 2010-08-04 | — | — | EP | claimed |
| US-20090118305-A1 | PYRIDINE AND PYRAZINE DERIVATIVES - 083 | ASTRAZENECA AB (SE) | 2009-05-07 | — | — | US | claimed |
| WO-2009053737-A2 | PYRIDINE AND PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2009-04-30 | — | — | WO | claimed |
| WO-2009024824-A1 | 2-ANILINOPURIN-8-ONES AS INHIBITORS OF TTK/MPS1 FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | claimed |
| CN-1252051-C | Positron emitted computerized tomography imaging agent benzamide derivative synthesizing method | JIANGSU PROV ATOMIC MEDICAL IN (CN) | 2006-04-19 | — | — | CN | claimed |
| EP-0391169-A2 | Enantiomeric pure 7-(3-amino-1-pyrrolidinyl)-chinolon-and-naphthyridon carboxylic acids | BAYER AG (DE) | 1990-10-10 | — | — | EP | claimed |