Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.69 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16486603 | 0.82 | TLR8 (1.00) | TLR8CXCR4PDE4BPOLB | |
| SCHEMBL16486950 | 0.81 | TLR8 (1.00) | TLR8CXCR4TP53POLB | |
| SCHEMBL16487216 | 0.80 | TLR8 (1.00) | TLR8CXCR4POLB | |
| SCHEMBL16512953 | 0.80 | TLR8 (0.74) | TLR8CXCR4POLB | |
| SCHEMBL16512951 | 0.80 | TLR8 (0.74) | TLR8CXCR4POLB | |
| SCHEMBL16512962 | 0.80 | TLR8 (1.00) | TLR8CXCR4TP53POLB | |
| SCHEMBL16512952 | 0.80 | TLR8 (0.74) | TLR8CXCR4POLB | |
| SCHEMBL16512712 | 0.80 | TLR8 (0.74) | TLR8CXCR4TP53POLB | |
| SCHEMBL16512958 | 0.77 | TLR8 (0.71) | TLR8CXCR4POLB | |
| SCHEMBL16512961 | 0.77 | TLR8 (1.00) | TLR8CXCR4TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10471139-B2 | Toll-like receptor agonists | THE UNIVERSITY OF KANSAS (US) | 2019-11-12 | — | — | US | disclosed |
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS | 2016-06-16 | — | — | US | disclosed |
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | TLR1, TLR7, TLR8 | TLR8 3/4885CXCR4 300/4885PDE4B 873/4885 |
| US-10471139-B2 | Toll-like receptor agonists | TLR1, TLR7, TLR8 | TLR8 3/4885CXCR4 300/4885PDE4B 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.