SCHEMBL17822757

SCHEMBL17822757

CC(N)C(=O)Nc1ccc(CO)c(I)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TAAR1 Q96RJ0 2/20 0.48
▸ TERT O14746 2/20 0.43
▸ LTA4H P09960 1/20 0.43
▸ IDO1 P14902 2/20 0.41
▸ KMT2A Q03164 3/20 0.40
▸ AAK1 Q2M2I8 1/20 0.39
▸ XIAP P98170 1/20 0.39
▸ CIT O14578 1/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ KDM4E B2RXH2 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ GLA P06280 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ CA12 O43570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17822756 1.00 TAAR1 (0.48) TAAR1TERTLTA4HIDO1KMT2A
SCHEMBL31045301 0.84 TAAR1 (0.49) TAAR1TERTLTA4HIDO1KMT2A
SCHEMBL28933879 0.82 HKDC1 (0.40) KMT2ANPC1MAPT
SCHEMBL31045361 0.82 TAAR1 (0.48) TAAR1TERTLTA4HIDO1KMT2A
SCHEMBL18245320 0.82 MAPT (0.42) KMT2AXIAPMEN1NPC1GAA
SCHEMBL22690281 0.79 TAAR1 (0.44) TAAR1TERTLTA4HIDO1KMT2A
SCHEMBL22690282 0.79 TAAR1 (0.44) TAAR1TERTLTA4HIDO1KMT2A
Hydrochloric Acid SCHEMBL30221757 0.78 TAAR1 (0.43) TAAR1TERTLTA4HIDO1KMT2A
SCHEMBL26689174 0.77 TAAR1 (0.46) TAAR1TERTLTA4HIDO1KMT2A
SCHEMBL26689173 0.77 TAAR1 (0.46) TAAR1TERTLTA4HIDO1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 — — US disclosed
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 — — US disclosed
EP-4364754-A2 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2024-05-08 — — EP disclosed
US-20240058450-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2024-02-22 — — US disclosed
CN-109963870-B anti-B7-H3 antibodies and antibody drug conjugates 艾伯维公司 2023-07-28 — — CN disclosed
CN-116284404-A anti-B7-H3 antibodies and antibody drug conjugates 艾伯维公司 2023-06-23 — — CN disclosed
CN-116173232-A anti-CD 98 antibodies and antibody drug conjugates 艾伯维公司 2023-05-30 — — CN disclosed
CN-116059201-A anti-EGFR antibody drug conjugates 艾伯维公司 2023-05-05 — — CN disclosed
CN-116059202-A anti-EGFR antibody drug conjugates 艾伯维公司 2023-05-05 — — CN disclosed
CN-116059394-A anti-EGFR antibody drug conjugates 艾伯维公司 2023-05-05 — — CN disclosed
EP-3468596-A2 ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2019-04-17 — — EP disclosed
EP-3468996-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2019-04-17 — — EP disclosed
EP-3458479-A1 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2019-03-27 — — EP disclosed
US-20170355769-A1 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE INC. 2017-12-14 — — US disclosed
WO-2017214462-A2 ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE INC. (US) 2017-12-14 — — WO disclosed
WO-2017214335-A1 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE INC. (US) 2017-12-14 — — WO disclosed
WO-2017214282-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC. (US) 2017-12-14 — — WO disclosed
EP-3230282-A1 BCL XL INHIBITORY COMPOUNDS HAVING LOW CELL PERMEABILITY AND ANTIBODY DRUG CONJUGATES INCLUDING THE SAME AbbVie Inc. (US) 2017-10-18 — — EP disclosed
US-20160339117-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC. (US) 2016-11-24 — — US disclosed
WO-2016094509-A1 BCL XL INHIBITORY COMPOUNDS HAVING LOW CELL PERMEABILITY AND ANTIBODY DRUG CONJUGATES INCLUDING THE SAME ABBVIE INC. (US) 2016-06-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 TAAR1 3576/4885TERT 4027/4885LTA4H 4457/4885
US-20170355769-A1 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES HRH3, H1-3, CD274 TAAR1 2494/4885TERT 4618/4885LTA4H 1195/4885
US-20160339117-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 TAAR1 4835/4885TERT 4079/4885LTA4H 4414/4885
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 TAAR1 4835/4885TERT 4079/4885LTA4H 4414/4885
US-20240058450-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 TAAR1 4835/4885TERT 4079/4885LTA4H 4414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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