Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.56 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.56 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Dimethoxybenzene SCHEMBL901285 | 0.97 | ACHE (0.70) | ACHEALDH1A1CYP3A4CA1CA2 | |
| 1,3-Dimethoxybenzene SCHEMBL9350 | 0.97 | ACHE (0.70) | ACHEALDH1A1CYP3A4CA1CA2 | |
| 1,3-Dimethoxybenzene SCHEMBL28068595 | 0.94 | ACHE (0.67) | ACHEALDH1A1CYP3A4CA1CA2 | |
| 1,3-Dimethoxybenzene SCHEMBL28135915 | 0.94 | ACHE (0.67) | ACHEALDH1A1CYP3A4CA1CA2 | |
| 1,3-Dimethoxybenzene SCHEMBL28262290 | 0.94 | ACHE (0.67) | ACHEALDH1A1CYP3A4CA1CA2 | |
| 1,3-Dimethoxybenzene SCHEMBL28542304 | 0.94 | ACHE (0.67) | ACHEALDH1A1CYP3A4CA1CA2 | |
| 1,3-Dimethoxybenzene SCHEMBL27850020 | 0.94 | ACHE (0.67) | ACHEALDH1A1CYP3A4CA1CA2 | |
| 1,3-Dimethoxybenzene SCHEMBL28343465 | 0.94 | ACHE (0.67) | ACHEALDH1A1CYP3A4CA1CA2 | |
| 1,3-Dimethoxybenzene SCHEMBL7860661 | 0.94 | ACHE (0.67) | ACHEALDH1A1CYP3A4CA1CA2 | |
| 1,3-Dimethoxybenzene SCHEMBL15870025 | 0.94 | ACHE (0.67) | ACHEALDH1A1CYP3A4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362263-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-12-21 | — | — | US | disclosed |
| EP-3230296-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | The Regents of The University of California (US) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016094489-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362263-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | PNKP, PLCB3, PLCB1 | ACHE 837/4885ALDH1A1 3148/4885CYP3A4 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.