Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250993 | 0.79 | CA2 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1547302 | 0.77 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL17525382 | 0.75 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL432539 | 0.75 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1044930 | 0.75 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1291912 | 0.75 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL774889 | 0.75 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL505777 | 0.75 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11158816 | 0.75 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1547876 | 0.75 | CA1 (0.50) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230296-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | The Regents of The University of California (US) | 2017-10-18 | — | — | EP | disclosed |
| CN-107250141-A | Phosphorus part and application method | 加利福尼亚大学董事会 | 2017-10-13 | — | — | CN | disclosed |
| WO-2016094489-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-06-16 | — | — | WO | disclosed |