SCHEMBL17824431

SCHEMBL17824431

OC[C@H]1O[C@@H](n2cnc3c(NCc4ccc(O)cc4)ncnc32)[C@@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 5/20 0.84
ADORA3 P0DMS8 2/20 0.83
TP53 P04637 1/20 0.83
TDP1 Q9NUW8 1/20 0.83
PRKAG1 P54619 1/20 0.81
PRKAA1 Q13131 1/20 0.81
PRKAB1 Q9Y478 1/20 0.81
ADORA2A P29274 1/20 0.73
ADORA1 P30542 1/20 0.73
PAX8 Q06710 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91088 1.00 SLC29A1 (0.84) SLC29A1ADORA3TP53TDP1PRKAG1
SCHEMBL639446 1.00 SLC29A1 (0.84) SLC29A1ADORA3TP53TDP1PRKAG1
SCHEMBL17825911 1.00 SLC29A1 (0.84) SLC29A1ADORA3TP53TDP1PRKAG1
SCHEMBL15189026 1.00 SLC29A1 (0.84) SLC29A1ADORA3TP53TDP1PRKAG1
SCHEMBL639447 1.00 SLC29A1 (0.84) SLC29A1ADORA3TP53TDP1PRKAG1
SCHEMBL75915 1.00 SLC29A1 (0.84) SLC29A1ADORA3TP53TDP1PRKAG1
SCHEMBL29697042 1.00 SLC29A1 (0.84) SLC29A1ADORA3TP53TDP1PRKAG1
SCHEMBL63259 1.00 SLC29A1 (0.84) SLC29A1ADORA3TP53TDP1PRKAG1
SCHEMBL20626300 1.00 SLC29A1 (0.84) SLC29A1ADORA3TP53TDP1PRKAG1
SCHEMBL25176169 0.99 SLC29A1 (0.82) SLC29A1ADORA3TP53TDP1PRKAG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3229771-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2024-04-03 EP claimed
EP-3229772-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2020-04-29 EP claimed
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2020-02-04 US claimed
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2018-10-16 US claimed
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-23 US claimed
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-16 US claimed
EP-3229771-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF Univerzita Palackého v Olomouci (CZ) 2017-10-18 EP claimed
WO-2016091235-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2016-06-16 WO claimed
EP-3229771-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2024-04-03 EP disclosed
EP-3229772-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2020-04-29 EP disclosed
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2020-02-04 US disclosed
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2018-10-16 US disclosed
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-23 US disclosed
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF GART, DAO, GLA SLC29A1 125/4885ADORA3 553/4885TP53 3135/4885
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof GART, DAO, GLA SLC29A1 125/4885ADORA3 553/4885TP53 3135/4885
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNG, FUT6, GART SLC29A1 59/4885ADORA3 387/4885TP53 2090/4885
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNG, FUT6, GART SLC29A1 59/4885ADORA3 387/4885TP53 2090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.