Inosine

Inosine

SCHEMBL17824478

O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Inosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP4 known ✓ P27487 1/20 0.67
▸ ADRB2 known ✓ P07550 1/20 0.58
▸ KCNH2 known ✓ Q12809 1/20 0.58
▸ SLC29A1 Q99808 4/20 0.67
▸ ADORA1 P30542 4/20 0.67
▸ SMN1; SMN2 Q16637 3/20 0.67
▸ ADORA3 P0DMS8 2/20 0.67
▸ MEN1 O00255 1/20 0.67
▸ SLC28A1 O00337 1/20 0.67
▸ MAP3K7 O43318 1/20 0.67
▸ SLC28A2 O43868 1/20 0.67
▸ GAPDH P04406 1/20 0.67
▸ MAPK1 P28482 1/20 0.67
▸ ADORA2A P29274 1/20 0.67
▸ ADORA2B P29275 1/20 0.67
▸ STAT6 P42226 1/20 0.67
▸ PI4KA P42356 1/20 0.67
▸ KMT2A Q03164 1/20 0.67
▸ PI4K2B Q8TCG2 1/20 0.67
▸ DOT1L Q8TEK3 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Inosine SCHEMBL1331735 1.00 SLC29A1 (0.67) SLC29A1ADORA1SMN1; SMN2ADORA3DPP4
Inosine SCHEMBL27486904 1.00 SLC29A1 (0.67) SLC29A1ADORA1SMN1; SMN2ADORA3DPP4
Inosine SCHEMBL29898199 1.00 SLC29A1 (0.67) SLC29A1ADORA1SMN1; SMN2ADORA3DPP4
Inosine SCHEMBL29941344 1.00 SLC29A1 (0.67) SLC29A1ADORA1SMN1; SMN2ADORA3DPP4
Inosine SCHEMBL5365023 1.00 SLC29A1 (0.67) SLC29A1ADORA1SMN1; SMN2ADORA3DPP4
Inosine SCHEMBL161317 1.00 SLC29A1 (0.67) SLC29A1ADORA1SMN1; SMN2ADORA3DPP4
Inosine SCHEMBL10622941 0.99 SLC29A1 (0.66) SLC29A1ADORA1SMN1; SMN2ADORA3DPP4
Inosine SCHEMBL19436352 0.99 ADORA1 (0.66) SLC29A1ADORA1SMN1; SMN2ADORA3DPP4
Inosine SCHEMBL311515 0.95 ADORA1 (0.68) SLC29A1ADORA1SMN1; SMN2ADORA3DPP4
Inosine SCHEMBL5905453 0.94 SLC29A1 (0.64) SLC29A1ADORA1SMN1; SMN2ADORA3DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095100-A Method for designing broad RNA modification library containing all surrounding sequences of RNA modification and use thereof — 2026-05-26 — — CN claimed
CN-106998771-B Flavour composition and pet food comprising same 马斯公司 2021-06-22 — — CN claimed
CN-122095100-A Method for designing broad RNA modification library containing all surrounding sequences of RNA modification and use thereof — 2026-05-26 — — CN disclosed
CN-118679161-A Methods of treating PTSD and neurological disorders GATC健康公司 2024-09-20 — — CN disclosed
CN-118678953-A Methods for treating addiction and neurological disorders GATC健康公司 2024-09-20 — — CN disclosed
EP-4403042-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2024-07-24 — — EP disclosed
EP-3229612-B1 USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2024-06-26 — — EP disclosed
CN-113717984-B Nucleic acid pesticide for resisting tobacco mosaic virus and synthesis, purification and application thereof 硅羿科技(上海)有限公司 2024-06-07 — — CN disclosed
CN-117222735-A Engineered acetate kinase variant enzymes 科德克希思公司 2023-12-12 — — CN disclosed
CN-117137048-A Flavor composition, food comprising the same, and method for increasing the flavor intensity of the umami taste of food 马斯公司 2023-12-01 — — CN disclosed
CN-117157397-A Engineered cyclic GMP-AMP synthase (cGAS) variant enzymes 科德克希思公司 2023-12-01 — — CN disclosed
CN-107249349-B Methods for modulating taste receptors 马斯公司 2021-06-08 — — CN disclosed
CN-111148846-A Method for capturing and barcoding discrete biological units in hydrogels 西比欧生物科学公司 2020-05-12 — — CN disclosed
US-20190021380-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2019-01-24 — — US disclosed
US-20180255813-A1 METHODS FOR MODULATING TASTE RECEPTORS MARS, INCORPORATED (US) 2018-09-13 — — US disclosed
US-20180168208-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2018-06-21 — — US disclosed
EP-3229606-A2 METHODS FOR MODULATING TASTE RECEPTORS Mars, Incorporated (US) 2017-10-18 — — EP disclosed
EP-3229610-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2017-10-18 — — EP disclosed
WO-2016094690-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 — — WO disclosed
WO-2016094702-A2 METHODS FOR MODULATING TASTE RECEPTORS MARS, INCORPORATED (US) 2016-06-16 — — WO disclosed
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