Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 3/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30591065 | 1.00 | PRMT1 (0.57) | PRMT1TMEM97SIGMAR1MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL29465555 | 0.99 | PRMT1 (0.56) | PRMT1TMEM97SIGMAR1MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL29456067 | 0.99 | PRMT1 (0.56) | PRMT1TMEM97SIGMAR1MEN1NPC1 | |
| SCHEMBL15432800 | 0.96 | TMEM97 (0.54) | PRMT1TMEM97SIGMAR1MEN1NPC1 | |
| SCHEMBL2614455 | 0.96 | TMEM97 (0.54) | PRMT1TMEM97SIGMAR1MEN1NPC1 | |
| SCHEMBL24227617 | 0.96 | TMEM97 (0.54) | PRMT1TMEM97SIGMAR1MEN1NPC1 | |
| SCHEMBL13736305 | 0.96 | TMEM97 (0.54) | PRMT1TMEM97SIGMAR1MEN1NPC1 | |
| SCHEMBL29576783 | 0.96 | TMEM97 (0.54) | PRMT1TMEM97SIGMAR1MEN1NPC1 | |
| SCHEMBL2614452 | 0.96 | TMEM97 (0.54) | PRMT1TMEM97SIGMAR1MEN1NPC1 | |
| SCHEMBL13736304 | 0.96 | TMEM97 (0.54) | PRMT1TMEM97SIGMAR1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-20200232023-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2020-07-23 | — | — | US | disclosed |
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-8729276-B2 | Cyanine compound for labeling biomolecule and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-05-20 | — | — | US | disclosed |
| US-20120095187-A1 | NOVEL CYANINE COMPOUND FOR LABELING BIOMOLECULE AND PREPARATION METHOD THEREOF | DKC CORPORATION (KR) | 2012-04-19 | — | — | US | disclosed |
| US-20120058469-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2012027618-A2 | FUNCTIONALIZED CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012027623-A2 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095187-A1 | NOVEL CYANINE COMPOUND FOR LABELING BIOMOLECULE AND PREPARATION METHOD THEREOF | MRPL21, MB, CCNB1 | PRMT1 5/4885TMEM97 3736/4885SIGMAR1 1788/4885 |
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | PRMT1 786/4885TMEM97 3170/4885SIGMAR1 1229/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | PRMT1 786/4885TMEM97 3170/4885SIGMAR1 1229/4885 |
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | PRMT1 786/4885TMEM97 3170/4885SIGMAR1 1229/4885 |
| US-20200232023-A1 | CYANINE DYES | ABCG2, IK, ACR | PRMT1 786/4885TMEM97 3170/4885SIGMAR1 1229/4885 |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | ACR, IK, EGFR | PRMT1 1260/4885TMEM97 1505/4885SIGMAR1 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.