SCHEMBL1782570

SCHEMBL1782570

CCCC(C)(COC(=O)c1ccccc1)COC(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.61
SLC6A3 Q01959 2/20 0.61
CYP2D6 P10635 2/20 0.61
HTR1A P08908 1/20 0.61
SCN1A P35498 1/20 0.61
SCN5A Q14524 1/20 0.61
SCN2A Q99250 1/20 0.61
SCN3A Q9NY46 1/20 0.61
MAPK1 P28482 1/20 0.61
HIF1A Q16665 1/20 0.61
LMNA P02545 2/20 0.59
HSD17B10 Q99714 2/20 0.51
ALDH1A1 P00352 3/20 0.50
KMT2A Q03164 3/20 0.50
TSHR P16473 3/20 0.47
SLC6A2 P23975 1/20 0.47
ADRB2 P07550 1/20 0.47
ADRB1 P08588 1/20 0.47
ADRB3 P13945 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL17996177 0.95 TDP1 (0.57) TDP1SLC6A3CYP2D6HTR1ASCN1A
SCHEMBL22666865 0.94 TDP1 (0.56) TDP1SLC6A3CYP2D6HTR1ASCN1A
SCHEMBL2020359 0.88 MAPK1 (0.71) TDP1SLC6A3CYP2D6HTR1ASCN1A
SCHEMBL570797 0.86 MAPK1 (0.65) TDP1SLC6A3CYP2D6HTR1ASCN1A
SCHEMBL12227603 0.85 MAPK1 (0.73) TDP1SLC6A3CYP2D6HTR1ASCN1A
SCHEMBL20854030 0.84 TDP1 (0.56) TDP1SLC6A3CYP2D6HTR1ASCN1A
SCHEMBL20854009 0.84 TDP1 (0.56) TDP1SLC6A3CYP2D6HTR1ASCN1A
SCHEMBL20854041 0.84 TDP1 (0.56) TDP1SLC6A3CYP2D6HTR1ASCN1A
SCHEMBL20854027 0.83 TDP1 (0.55) TDP1SLC6A3CYP2D6HTR1ASCN1A
SCHEMBL6053597 0.83 MAPK1 (0.65) TDP1SLC6A3CYP2D6HTR1ASCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841976-A Solid catalyst component for olefin polymerization, preparation method thereof, catalyst and application 中国石油化工股份有限公司 2025-04-18 CN claimed
CN-115975084-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2025-02-28 CN claimed
CN-115975075-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2024-09-17 CN claimed
CN-118290625-A Polypropylene and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN claimed
CN-118290623-A Polypropylene and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN claimed
CN-118290624-A Polypropylene and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN claimed
CN-117756970-A Catalyst for butene-1 polymerization and application thereof 中国石油化工股份有限公司 2024-03-26 CN claimed
CN-115975084-A Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2023-04-18 CN claimed
CN-115975075-A Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2023-04-18 CN claimed
CN-113444189-A Catalyst for olefin polymerization and application thereof 中国石油化工股份有限公司 2021-09-28 CN claimed
EP-3059264-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME CHINA PETROLEUM & CHEM CORP (CN) 2018-12-26 EP claimed
EP-3194483-B1 POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION EASTMAN CHEM CO (US) 2018-12-19 EP claimed
EP-3194483-A1 POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION Eastman Chemical Company (US) 2017-07-26 EP claimed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP claimed
US-20160264694-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-09-15 US claimed
EP-3059264-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME China Petroleum&Chemical Corporation (CN) 2016-08-24 EP claimed
WO-2016044230-A1 POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION EASTMAN CHEMICAL COMPANY (US) 2016-03-24 WO claimed
US-20160075857-A1 POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION EASTMAN CHEMICAL COMPANY (US) 2016-03-17 US claimed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US claimed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160075857-A1 POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION LRBA, FARSB, PUF60 TDP1 687/4885SLC6A3 4777/4885CYP2D6 4551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.