Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499232 | 0.80 | TSHR (0.41) | CYP19A1 | |
| SCHEMBL4592845 | 0.79 | SMN1; SMN2 (0.44) | CYP19A1 | |
| SCHEMBL5865736 | 0.74 | CYP19A1 (1.00) | CYP19A1CYP1A1 | |
| SCHEMBL9756477 | 0.74 | CYP19A1 (0.56) | CYP19A1CYP1A1 | |
| SCHEMBL5782527 | 0.73 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL27494651 | 0.72 | CYP19A1 (0.57) | CYP19A1 | |
| SCHEMBL5972481 | 0.72 | CYP19A1 (0.57) | CYP19A1 | |
| SCHEMBL3579264 | 0.72 | CYP19A1 (0.53) | CYP19A1CYP1A1 | |
| SCHEMBL11015925 | 0.72 | CYP19A1 (0.67) | CYP19A1CYP1A1 | |
| SCHEMBL29471930 | 0.72 | CYP19A1 (0.67) | CYP19A1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229801-A1 | FACTOR IXA INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016094260-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-16 | — | — | WO | disclosed |
| CN-101223143-A | 3-cyanoquinoline inhibitors of TPL2 kinase and methods of making and using the same | WYETH CORP (US) | 2008-07-16 | — | — | CN | disclosed |