SCHEMBL9756477

SCHEMBL9756477

O=C(O)CC(c1ccccc1)n1ccnn1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 12/20 0.56
POLB P06746 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP1A1 P04798 2/20 0.46
HSD17B10 Q99714 1/20 0.44
CYP2C19 P33261 2/20 0.44
GABBR2 O75899 1/20 0.44
GABBR1 Q9UBS5 1/20 0.44
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
HMOX2 P30519 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20773275 0.80 CYP19A1 (0.62) CYP19A1CYP1A1
SCHEMBL29273163 0.79 CYP19A1 (0.57) CYP19A1CYP1A1
SCHEMBL27621980 0.79 POLB (0.45) POLBSMN1; SMN2TDP1HSD17B10CYP2C19
SCHEMBL27647784 0.79 CYP19A1 (0.49) CYP19A1SMN1; SMN2CYP1A1
SCHEMBL29471928 0.76 CYP19A1 (0.57) CYP19A1CYP1A1
SCHEMBL29378914 0.76 CYP19A1 (0.57) CYP19A1CYP1A1
SCHEMBL17825837 0.74 CYP19A1 (0.59) CYP19A1CYP1A1
SCHEMBL20773598 0.74 CYP19A1 (0.50) CYP19A1CYP1A1
SCHEMBL9575031 0.73 HSD17B10 (0.75) POLBSMN1; SMN2TDP1HSD17B10CYP2C19
SCHEMBL401391 0.73 CYP19A1 (0.53) CYP19A1CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0432212-A1 HERBICIDAL TRIAZOLINONES. FMC CORP (US) 1991-06-19 EP disclosed
WO-1990002120-A1 HERBICIDAL TRIAZOLINONES FMC CORPORATION (US) 1990-03-08 WO disclosed