Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.77 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.77 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.77 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.71 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.71 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17824381 | 1.00 | ADORA3 (0.77) | ADORA3ADORA1ADORA2AADORA2BTP53 | |
| SCHEMBL638672 | 1.00 | ADORA3 (0.77) | ADORA3ADORA1ADORA2AADORA2BTP53 | |
| SCHEMBL638673 | 1.00 | ADORA3 (0.77) | ADORA3ADORA1ADORA2AADORA2BTP53 | |
| SCHEMBL25170475 | 0.99 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AADORA2BTP53 | |
| SCHEMBL640553 | 0.92 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AADORA2BTP53 | |
| SCHEMBL640552 | 0.92 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AADORA2BTP53 | |
| SCHEMBL27881272 | 0.92 | ADORA2A (0.76) | ADORA3ADORA1ADORA2A | |
| SCHEMBL639730 | 0.91 | ADORA3 (0.72) | ADORA3ADORA1ADORA2AADORA2BTP53 | |
| SCHEMBL19582992 | 0.91 | ADORA3 (0.72) | ADORA3ADORA1ADORA2AADORA2BTP53 | |
| SCHEMBL639729 | 0.91 | ADORA3 (0.72) | ADORA3ADORA1ADORA2AADORA2BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229772-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | Univerzita Palackého v Olomouci (CZ) | 2017-10-18 | — | — | EP | claimed |
| WO-2016091236-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-16 | — | — | WO | claimed |
| EP-3229772-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | Univerzita Palackého v Olomouci (CZ) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016091236-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-16 | — | — | WO | disclosed |